The Ghosh Lab studies the mechanisms that regulate the specification of connections in the developing cerebral cortex. There are two major areas of research in the lab. First, we are investigating the mechanisms that regulate synapse formation and synaptic specificity in the developing cortex.

The goal of these experiments is to identify signals that allow neurons to select appropriate synaptic partners and to understand how synaptic components are recruited to a developing synapse. Second, we are exploring the mechanisms by which synaptic activity influences the assembly and plasticity of neural circuits. These experiments are directed towards understanding how calcium signaling regulates neuronal morphology and the formation of functional connections. Please check out the links on this page to learn more about our past and present research.